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Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis

BACKGROUND AND AIMS: Previous studies modelling human neural crest differentiation from stem cells have resulted in a low yield of sympathetic neurons. Our aim was to optimise a method for the differentiation of human embryonic stem cells (hESCs) to sympathetic neuron-like cells (SN) to model normal...

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Detalles Bibliográficos
Autores principales: Carr-Wilkinson, Jane, Prathalingam, Nilendran, Pal, Deepali, Moad, Mohammad, Lee, Natalie, Sundaresh, Aishwarya, Forgham, Helen, James, Peter, Herbert, Mary, Lako, Majlinda, Tweddle, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236576/
https://www.ncbi.nlm.nih.gov/pubmed/30515222
http://dx.doi.org/10.1155/2018/4391641