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S-Allyl Cysteine Alleviates Hydrogen Peroxide Induced Oxidative Injury and Apoptosis through Upregulation of Akt/Nrf-2/HO-1 Signaling Pathway in HepG2 Cells

Hydrogen peroxide (H(2)O(2)) mediated oxidative stress leading to hepatocyte apoptosis plays a pivotal role in the pathophysiology of several chronic liver diseases. This study demonstrates that S-allyl cysteine (SAC) renders cytoprotective effects on H(2)O(2) induced oxidative damage and apoptosis...

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Detalles Bibliográficos
Autores principales: Basu, Chitra, Sur, Runa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236807/
https://www.ncbi.nlm.nih.gov/pubmed/30515391
http://dx.doi.org/10.1155/2018/3169431