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Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

BACKGROUND: La Crosse virus (LACV) causes pediatric encephalitis in the USA. LACV induces severe inflammation in the central nervous system, but the recruitment of inflammatory cells is poorly understood. A deeper understanding of LACV-induced neural pathology is needed in order to develop treatment...

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Detalles Bibliográficos
Autores principales: Dawes, Brian E., Gao, Junling, Atkins, Colm, Nelson, Jacob T., Johnson, Kendra, Wu, Ping, Freiberg, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236894/
https://www.ncbi.nlm.nih.gov/pubmed/30442185
http://dx.doi.org/10.1186/s12974-018-1356-5