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Varicella zoster virus differentially alters morphology and suppresses proinflammatory cytokines in primary human spinal cord and hippocampal astrocytes

BACKGROUND: Varicella zoster virus (VZV) is a ubiquitous alphaherpesvirus that produces varicella and zoster. VZV can infect multiple cell types in the spinal cord and brain, including astrocytes, producing myelopathy and encephalopathy. While studies of VZV-astrocyte interactions are sparse, a rece...

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Detalles Bibliográficos
Autores principales: Bubak, Andrew N., Como, Christina N., Blackmon, Anna M., Jones, Dallas, Nagel, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236967/
https://www.ncbi.nlm.nih.gov/pubmed/30442152
http://dx.doi.org/10.1186/s12974-018-1360-9