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Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer

BACKGROUND: While self-reported exercise is associated with a reduction in the risk of recurrence in colorectal cancer, the molecular mechanisms underpinning this relationship are unknown. Furthermore, the effect of exercise on intratumoral metabolic processes has not been investigated in detail in...

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Detalles Bibliográficos
Autores principales: Lu, Min, Sanderson, Sydney M, Zessin, Amelia, Ashcraft, Kathleen A, Jones, Lee W, Dewhirst, Mark W, Locasale, Jason W, Hsu, David S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237036/
https://www.ncbi.nlm.nih.gov/pubmed/30473788
http://dx.doi.org/10.1186/s40170-018-0190-7