Multiple Critical Periods for Rapamycin Treatment to Correct Structural Defects in Tsc-1-Suppressed Brain

Tuberous sclerosis complex (TSC) is an autosomal dominant neurogenetic disorder affecting the brain and other vital organs. Neurological symptoms include epilepsy, intellectual disability, and autism. TSC is caused by a loss-of-function mutation in the TSC1 or TSC2 gene. These gene products form a p...

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Detalles Bibliográficos
Autores principales: Cox, Rebecca L., Calderon de Anda, Froylan, Mangoubi, Tomer, Yoshii, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237075/
https://www.ncbi.nlm.nih.gov/pubmed/30467464
http://dx.doi.org/10.3389/fnmol.2018.00409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237075/
https://www.ncbi.nlm.nih.gov/pubmed/30467464
http://dx.doi.org/10.3389/fnmol.2018.00409

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