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A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

Background: We established an in vitro co-culture model involving H3N2-infection of human nasal epithelium with peripheral blood mononuclear cells (PBMC) to investigate their cross-talk during early H3N2 infection. Methods: Nasal epithelium was differentiated from human nasal epithelial stem/progeni...

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Detalles Bibliográficos
Autores principales: Luukkainen, Annika, Puan, Kia Joo, Yusof, Nurhashikin, Lee, Bernett, Tan, Kai Sen, Liu, Jing, Yan, Yan, Toppila-Salmi, Sanna, Renkonen, Risto, Chow, Vincent T., Rotzschke, Olaf, Wang, De Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237251/
https://www.ncbi.nlm.nih.gov/pubmed/30467502
http://dx.doi.org/10.3389/fimmu.2018.02514