Evaluation of the capacities of mouse TCR profiling from short read RNA-seq data

Profiling T cell receptor (TCR) repertoire via short read transcriptome sequencing (RNA-Seq) has a unique advantage of probing simultaneously TCRs and the genome-wide RNA expression of other genes. However, compared to targeted amplicon approaches, the shorter read length is more prone to mapping er...

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Detalles Bibliográficos
Autores principales: Bai, Yu, Wang, David, Li, Wentian, Huang, Ying, Ye, Xuan, Waite, Janelle, Barry, Thomas, Edelmann, Kurt H., Levenkova, Natasha, Guo, Chunguang, Skokos, Dimitris, Wei, Yi, Macdonald, Lynn E., Fury, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237323/
https://www.ncbi.nlm.nih.gov/pubmed/30439982
http://dx.doi.org/10.1371/journal.pone.0207020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237323/
https://www.ncbi.nlm.nih.gov/pubmed/30439982
http://dx.doi.org/10.1371/journal.pone.0207020

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