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Generation of an inducible RPE-specific Cre transgenic-mouse line

The retinal pigment epithelium (RPE) is an epithelial monolayer in the back of the vertebrate eye. RPE dysfunction is associated with retinal degeneration and blindness. In order to fully understand how dysregulation affects visual function, RPE-specific gene knockouts are indispensable. Since the c...

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Detalles Bibliográficos
Autores principales: Schneider, Sandra, Hotaling, Nathan, Campos, Maria, Patnaik, Sarita Rani, Bharti, Kapil, May-Simera, Helen Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237357/
https://www.ncbi.nlm.nih.gov/pubmed/30440011
http://dx.doi.org/10.1371/journal.pone.0207222