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Generation of an inducible RPE-specific Cre transgenic-mouse line
The retinal pigment epithelium (RPE) is an epithelial monolayer in the back of the vertebrate eye. RPE dysfunction is associated with retinal degeneration and blindness. In order to fully understand how dysregulation affects visual function, RPE-specific gene knockouts are indispensable. Since the c...
Autores principales: | Schneider, Sandra, Hotaling, Nathan, Campos, Maria, Patnaik, Sarita Rani, Bharti, Kapil, May-Simera, Helen Louise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237357/ https://www.ncbi.nlm.nih.gov/pubmed/30440011 http://dx.doi.org/10.1371/journal.pone.0207222 |
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