Yeast XRS2 and human NBN gene: Experimental evidence for homology using codon optimized cDNA

The genes, XRS2 in Saccharomyces cerevisiae and NBN in mammals, have little sequence identity at the amino acid level. Nevertheless, they are both found together with MRE11 and RAD50 in a highly conserved protein complex which functions in the repair of DNA double-strand breaks. Here, we have examin...

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Detalles Bibliográficos
Autores principales: Demuth, Ilja, Krebs, Simon K., Dutrannoy, Véronique, Linke, Christian, Krobitsch, Sylvia, Varon, Raymonda, Lang, Christine, Raab, Andreas, Sperling, Karl, Digweed, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237358/
https://www.ncbi.nlm.nih.gov/pubmed/30440001
http://dx.doi.org/10.1371/journal.pone.0207315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237358/
https://www.ncbi.nlm.nih.gov/pubmed/30440001
http://dx.doi.org/10.1371/journal.pone.0207315

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