Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes

Antigenic variation by variant surface glycoprotein (VSG) coat switching in African trypanosomes is one of the most elaborate immune evasion strategies found among pathogens. Changes in the identity of the transcribed VSG gene, which is always flanked by 70-bp and telomeric repeats, can be achieved...

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Detalles Bibliográficos
Autores principales: da Silva, Marcelo Santos, Hovel-Miner, Galadriel A., Briggs, Emma M., Elias, Maria Carolina, McCulloch, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237402/
https://www.ncbi.nlm.nih.gov/pubmed/30440029
http://dx.doi.org/10.1371/journal.ppat.1007321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237402/
https://www.ncbi.nlm.nih.gov/pubmed/30440029
http://dx.doi.org/10.1371/journal.ppat.1007321

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