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Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes
Antigenic variation by variant surface glycoprotein (VSG) coat switching in African trypanosomes is one of the most elaborate immune evasion strategies found among pathogens. Changes in the identity of the transcribed VSG gene, which is always flanked by 70-bp and telomeric repeats, can be achieved...
Autores principales: | da Silva, Marcelo Santos, Hovel-Miner, Galadriel A., Briggs, Emma M., Elias, Maria Carolina, McCulloch, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237402/ https://www.ncbi.nlm.nih.gov/pubmed/30440029 http://dx.doi.org/10.1371/journal.ppat.1007321 |
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