Synthetic protein alignments by CCMgen quantify noise in residue-residue contact prediction

Compensatory mutations between protein residues in physical contact can manifest themselves as statistical couplings between the corresponding columns in a multiple sequence alignment (MSA) of the protein family. Conversely, large coupling coefficients predict residue contacts. Methods for de-novo p...

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Detalles Bibliográficos
Autores principales: Vorberg, Susann, Seemayer, Stefan, Söding, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237422/
https://www.ncbi.nlm.nih.gov/pubmed/30395601
http://dx.doi.org/10.1371/journal.pcbi.1006526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237422/
https://www.ncbi.nlm.nih.gov/pubmed/30395601
http://dx.doi.org/10.1371/journal.pcbi.1006526

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