Upregulation of AMPK by 4‐O‐methylascochlorin promotes autophagy via the HIF‐1α expression

4‐O‐methylascochlorin (MAC) is a derivative of ascochlorin, a prenyl‐phenol compound antibiotic isolated from the fungus Ascochyta viciae. MAC induces caspase/poly (ADP‐ribose) polymerase‐mediated apoptosis in leukemia cells. However, the effects of MAC on autophagy in cancer cells and the underlyin...

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Detalles Bibliográficos
Autores principales: Seok, Ji‐Young, Jeong, Yun‐Jeong, Hwang, Soon‐Kyung, Kim, Cheorl‐Ho, Magae, Junji, Chang, Young‐Chae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237564/
https://www.ncbi.nlm.nih.gov/pubmed/30338933
http://dx.doi.org/10.1111/jcmm.13933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237564/
https://www.ncbi.nlm.nih.gov/pubmed/30338933
http://dx.doi.org/10.1111/jcmm.13933

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