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Upregulation of AMPK by 4‐O‐methylascochlorin promotes autophagy via the HIF‐1α expression
4‐O‐methylascochlorin (MAC) is a derivative of ascochlorin, a prenyl‐phenol compound antibiotic isolated from the fungus Ascochyta viciae. MAC induces caspase/poly (ADP‐ribose) polymerase‐mediated apoptosis in leukemia cells. However, the effects of MAC on autophagy in cancer cells and the underlyin...
Autores principales: | Seok, Ji‐Young, Jeong, Yun‐Jeong, Hwang, Soon‐Kyung, Kim, Cheorl‐Ho, Magae, Junji, Chang, Young‐Chae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237564/ https://www.ncbi.nlm.nih.gov/pubmed/30338933 http://dx.doi.org/10.1111/jcmm.13933 |
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