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MYC and DNMT3A‐mediated DNA methylation represses microRNA‐200b in triple negative breast cancer

Triple‐negative breast cancer (TNBC) is the most aggressive breast cancer subtype with a poor prognosis. The microRNA‐200 (miR‐200) family has been associated with breast cancer metastasis. However, the epigenetic mechanisms underlying miR‐200b repression in TNBC are not fully elucidated. In this st...

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Detalles Bibliográficos
Autores principales: Pang, Yamei, Liu, Jian, Li, Xiang, Xiao, Guodong, Wang, Huangzhen, Yang, Ganghua, Li, Yanbo, Tang, Shou‐Ching, Qin, Sida, Du, Ning, Zhang, Henggang, Liu, Dapeng, Sun, Xin, Ren, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237581/
https://www.ncbi.nlm.nih.gov/pubmed/30324719
http://dx.doi.org/10.1111/jcmm.13916