An alternative renin isoform is cardioprotective by modulating mitochondrial metabolism

The renin‐angiotensin system promotes oxidative stress, apoptosis, necrosis, fibrosis, and thus heart failure. Secretory renin plays a central role in these processes, initiating the generation of angiotensins. Nevertheless, alternative renin transcripts exist, which code for a cytosolically localiz...

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Detalles Bibliográficos
Autores principales: Wanka, Heike, Lutze, Philipp, Staar, Doreen, Grunow, Bianka, Peters, Barbara S., Peters, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237583/
https://www.ncbi.nlm.nih.gov/pubmed/30247805
http://dx.doi.org/10.1111/jcmm.13872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237583/
https://www.ncbi.nlm.nih.gov/pubmed/30247805
http://dx.doi.org/10.1111/jcmm.13872

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