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Inhibition of autophagy enhances the antitumour activity of tigecycline in multiple myeloma

Accumulating evidence shows that tigecycline, a first‐in‐class glycylcycline, has potential antitumour properties. Here, we found that tigecycline dramatically inhibited the proliferation of multiple myeloma (MM) cell lines RPMI‐8226, NCI‐H929 and U266 in a dose and time‐dependent manner. Meanwhile,...

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Detalles Bibliográficos
Autores principales: Ma, Ruye, Zhang, Yu, Wang, Wei, Wu, Junqing, Yang, Qianqian, Xu, Wanling, Jiang, Songfu, Han, Yixiang, Yu, Kang, Zhang, Shenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237591/
https://www.ncbi.nlm.nih.gov/pubmed/30247801
http://dx.doi.org/10.1111/jcmm.13865