Cargando…

HMGB1 deficiency reduces H(2)O(2)‐induced oxidative damage in human melanocytes via the Nrf2 pathway

Oxidative stress leads to melanocyte death and has been implicated in the pathogenesis of vitiligo. The nuclear factor, E2‐related factor 2 (Nrf2), is a critical transcription factor in protecting cells from oxidative damage. High‐mobility group box 1 (HMGB1) is a chromatin‐associated nuclear protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Mou, Kuanhou, Liu, Wei, Miao, Yi, Cao, Fang, Li, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237592/
https://www.ncbi.nlm.nih.gov/pubmed/30338917
http://dx.doi.org/10.1111/jcmm.13895