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Changes in cell differentiation and proliferation lead to production of abzymes in EAE mice treated with DNA–Histone complexes

Experimental autoimmune encephalomyelitis (EAE)‐prone C57BL/6 mice are used as a model of human multiple sclerosis. We immunize mice with myelin oligodendrocyte glycoprotein (MOG), DNA–histone and DNA‐methylated bovine serum albumin (met‐BSA) complexes to reveal different characteristics of EAE deve...

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Detalles Bibliográficos
Autores principales: Aulova, Kseniya S., Toporkova, Ludmila B., Lopatnikova, Julia A., Alshevskaya, Alina A., Sedykh, Sergey E., Buneva, Valentina N., Budde, Thomas, Meuth, Sven G., Popova, Nelly A., Orlovskaya, Irina A., Nevinsky, Georgy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237594/
https://www.ncbi.nlm.nih.gov/pubmed/30265424
http://dx.doi.org/10.1111/jcmm.13850