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Adenosine deaminase inhibition suppresses progression of 4T1 murine breast cancer by adenosine receptor‐dependent mechanisms

The activity of a cell‐surface ecto‐adenosine deaminase (eADA) is markedly increased in the endothelial activation and vascular inflammation leading to decreased adenosine concentration and alterations in adenosine signalling. Depending on the specific pathway activated, extracellular purines mediat...

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Detalles Bibliográficos
Autores principales: Kutryb‐Zajac, Barbara, Koszalka, Patrycja, Mierzejewska, Paulina, Bulinska, Alicja, Zabielska, Magdalena A., Brodzik, Karolina, Skrzypkowska, Aleksandra, Zelazek, Lukasz, Pelikant‐Malecka, Iwona, Slominska, Ewa M., Smolenski, Ryszard T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237598/
https://www.ncbi.nlm.nih.gov/pubmed/30291675
http://dx.doi.org/10.1111/jcmm.13864