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Targeting c‐met receptor tyrosine kinase by the DNA aptamer SL1 as a potential novel therapeutic option for myeloma

Hepatocyte growth factor (HGF)/c‐met pathway activation has been implicated in the pathogenesis of multiple myeloma (MM), and blocking this pathway has been considered a rational therapeutic strategy for treating MM. Aptamers are single‐stranded nucleic acid molecules that fold into complex 3D struc...

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Detalles Bibliográficos
Autores principales: Zhang, Yibin, Gao, Hongmei, Zhou, Weihua, Sun, Sunming, Zeng, Yayue, Zhang, Hui, Liang, Long, Xiao, Xiaojuan, Song, Jianhui, Ye, Mao, Yang, Yujia, Zhao, Jingfeng, Wang, Zi, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237600/
https://www.ncbi.nlm.nih.gov/pubmed/30353654
http://dx.doi.org/10.1111/jcmm.13870