PML‐RARα interferes with erythropoiesis by repressing LMO2 in acute promyelocytic leukaemia

The PML‐RARα fusion gene, generated by the t(15;17) chromosome translocation, is regarded as the initiating factor of acute promyelocytic leukaemia (APL). In addition to the well‐known effects on blocking myeloid differentiation at the promyelocytic stage, promyelocytic leukaemia‐retinoic acid recep...

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Detalles Bibliográficos
Autores principales: Yang, Xianwen, Tan, Yun, Wang, Ping, Zhang, Hui, Zhao, Ming, Zhao, Xujie, Wang, Kankan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237603/
https://www.ncbi.nlm.nih.gov/pubmed/30320491
http://dx.doi.org/10.1111/jcmm.13917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237603/
https://www.ncbi.nlm.nih.gov/pubmed/30320491
http://dx.doi.org/10.1111/jcmm.13917

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