Cargando…
Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation
The mammary luminal lineage relies on the common cytokine-sensing transcription factor STAT5 to establish super-enhancers during pregnancy and initiate a genetic program that activates milk production. As pups grow, the greatly increasing demand for milk requires progressive differentiation of mamma...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237736/ https://www.ncbi.nlm.nih.gov/pubmed/30285185 http://dx.doi.org/10.1093/nar/gky891 |