Mathematical modeling identifies potential gene structure determinants of co-transcriptional control of alternative pre-mRNA splicing

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The spliceosome catalyzes the removal of introns from pre-messenger RNA (mRNA) and subsequent pairing of exons with remarkable fidelity. Some exons are known to be skipped or included in the mature mRNA in a cell type- or context-dependent manner (cassette exons), thereby contributing to the diversi...

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Detalles Bibliográficos
Autores principales: Davis-Turak, Jeremy, Johnson, Tracy L, Hoffmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237756/
https://www.ncbi.nlm.nih.gov/pubmed/30272246
http://dx.doi.org/10.1093/nar/gky870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237756/
https://www.ncbi.nlm.nih.gov/pubmed/30272246
http://dx.doi.org/10.1093/nar/gky870

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