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Mathematical modeling identifies potential gene structure determinants of co-transcriptional control of alternative pre-mRNA splicing
The spliceosome catalyzes the removal of introns from pre-messenger RNA (mRNA) and subsequent pairing of exons with remarkable fidelity. Some exons are known to be skipped or included in the mature mRNA in a cell type- or context-dependent manner (cassette exons), thereby contributing to the diversi...
Autores principales: | Davis-Turak, Jeremy, Johnson, Tracy L, Hoffmann, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237756/ https://www.ncbi.nlm.nih.gov/pubmed/30272246 http://dx.doi.org/10.1093/nar/gky870 |
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