Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway

Mucins are heavily glycosylated proteins that play critical roles in the pathogenesis of tumour malignancies. Pancreatic ductal adenocarcinoma (PDAC) is characterised by the aberrant expression of mucins. However, the role of mucin (MUC) 20 in PDAC remains unclear. PDAC is usually surrounded by a de...

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Detalles Bibliográficos
Autores principales: Chen, Syue-Ting, Kuo, Ting-Chun, Liao, Ying-Yu, Lin, Mei-Chun, Tien, Yu-Wen, Huang, Min-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237765/
https://www.ncbi.nlm.nih.gov/pubmed/29993037
http://dx.doi.org/10.1038/s41388-018-0403-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237765/
https://www.ncbi.nlm.nih.gov/pubmed/29993037
http://dx.doi.org/10.1038/s41388-018-0403-0

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