Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

MutS homologs identify base-pairing errors made in DNA during replication and initiate their repair. In the presence of adenosine triphosphate, MutS induces DNA bending upon mismatch recognition and subsequently undergoes conformational transitions that promote its interaction with MutL to signal re...

Descripción completa

Detalles Bibliográficos
Autores principales: LeBlanc, Sharonda J, Gauer, Jacob W, Hao, Pengyu, Case, Brandon C, Hingorani, Manju M, Weninger, Keith R, Erie, Dorothy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237781/
https://www.ncbi.nlm.nih.gov/pubmed/30272207
http://dx.doi.org/10.1093/nar/gky865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237781/
https://www.ncbi.nlm.nih.gov/pubmed/30272207
http://dx.doi.org/10.1093/nar/gky865

Ejemplares similares