Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity

Retroviruses package two complete RNA genomes into a viral particle but generate only one provirus after each infection. This pseudodiploid replication strategy facilitates frequent recombination, which occurs during DNA synthesis when reverse transcriptase switches templates between two copackaged...

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Detalles Bibliográficos
Autores principales: Rawson, Jonathan M O, Nikolaitchik, Olga A, Keele, Brandon F, Pathak, Vinay K, Hu, Wei-Shau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237782/
https://www.ncbi.nlm.nih.gov/pubmed/30307534
http://dx.doi.org/10.1093/nar/gky910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237782/
https://www.ncbi.nlm.nih.gov/pubmed/30307534
http://dx.doi.org/10.1093/nar/gky910

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