Cargando…

Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity

Retroviruses package two complete RNA genomes into a viral particle but generate only one provirus after each infection. This pseudodiploid replication strategy facilitates frequent recombination, which occurs during DNA synthesis when reverse transcriptase switches templates between two copackaged...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rawson, Jonathan M O, Nikolaitchik, Olga A, Keele, Brandon F, Pathak, Vinay K, Hu, Wei-Shau
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237782/ https://www.ncbi.nlm.nih.gov/pubmed/30307534 http://dx.doi.org/10.1093/nar/gky910

Ejemplares similares

A phage parasite deploys a nicking nuclease effector to inhibit viral host replication
por: LeGault, Kristen N, et al.
Publicado: (2022)

Adenovirus prevents dsRNA formation by promoting efficient splicing of viral RNA
por: Price, Alexander M, et al.
Publicado: (2021)

CtIP is essential for telomere replication
por: Stroik, Susanna, et al.
Publicado: (2019)

CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance
por: Feng, Xuyang, et al.
Publicado: (2017)

The FANCC–FANCE–FANCF complex is evolutionarily conserved and regulates meiotic recombination
por: Singh, Dipesh Kumar, et al.
Publicado: (2023)

HIBLUP: an integration of statistical models on the BLUP framework for efficient genetic evaluation using big genomic data
por: Yin, Lilin, et al.
Publicado: (2023)

The Fkh1 Forkhead associated domain promotes ORC binding to a subset of DNA replication origins in budding yeast
por: Hoggard, Timothy, et al.
Publicado: (2021)

The S. cerevisiae m(6)A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts
por: Scutenaire, Jérémy, et al.
Publicado: (2022)

The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis
por: Bao, Jianqiang, et al.
Publicado: (2018)

A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies
por: Xu, Jing, et al.
Publicado: (2021)

Designer tRNAs for efficient incorporation of non-canonical amino acids by the pyrrolysine system in mammalian cells
por: Serfling, Robert, et al.
Publicado: (2018)

Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect
por: El Kazzi, Priscila, et al.
Publicado: (2022)

microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development
por: Mayya, Vinay K, et al.
Publicado: (2021)

Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription
por: Belashov, Ivan A, et al.
Publicado: (2018)

A pan-cancer atlas of somatic mutations in miRNA biogenesis genes
por: Galka-Marciniak, Paulina, et al.
Publicado: (2021)

Identification of mechanism of cancer-cell-specific reactivation of hTERT offers therapeutic opportunities for blocking telomerase specifically in human colorectal cancer
por: Akıncılar, Semih Can, et al.
Publicado: (2022)

Prespacer processing and specific integration in a Type I-A CRISPR system
por: Rollie, Clare, et al.
Publicado: (2018)

The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease
por: Noronha, Alberto, et al.
Publicado: (2019)

Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons
por: Sakai, Yusuke, et al.
Publicado: (2016)

Automated physics-based design of synthetic riboswitches from diverse RNA aptamers
por: Espah Borujeni, Amin, et al.
Publicado: (2016)

The STAR protein QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs
por: Yamagishi, Ryota, et al.
Publicado: (2016)

Identification of a mismatch-specific endonuclease in hyperthermophilic Archaea
por: Ishino, Sonoko, et al.
Publicado: (2016)

Reversible acetylation on Lys501 regulates the activity of RNase II
por: Song, Limin, et al.
Publicado: (2016)

Methylation of histone H3 lysine 9 occurs during translation
por: Rivera, Carlos, et al.
Publicado: (2015)

Structure of a human translation termination complex
por: Matheisl, Sarah, et al.
Publicado: (2015)

Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse
por: Depreux, Frederic F., et al.
Publicado: (2016)

A novel role for poly(C) binding proteins in programmed ribosomal frameshifting
por: Napthine, Sawsan, et al.
Publicado: (2016)

High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy
por: Short, Judith M., et al.
Publicado: (2016)

Mitochondrial DNA exhibits resistance to induced point and deletion mutations
por: Valente, William J., et al.
Publicado: (2016)

3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM
por: Chua, Eugene Y.D., et al.
Publicado: (2016)

Division of labor among Mycobacterium smegmatis RNase H enzymes: RNase H1 activity of RnhA or RnhC is essential for growth whereas RnhB and RnhA guard against killing by hydrogen peroxide in stationary phase
por: Gupta, Richa, et al.
Publicado: (2017)

DNA-assisted oligomerization of pore-forming toxin monomers into precisely-controlled protein channels
por: Henning-Knechtel, Anja, et al.
Publicado: (2017)

A single active site in the mariner transposase cleaves DNA strands of opposite polarity
por: Claeys Bouuaert, Corentin, et al.
Publicado: (2017)

The mechanisms of a mammalian splicing enhancer
por: Jobbins, Andrew M, et al.
Publicado: (2018)

Logical engineering of D-arm and T-stem of tRNA that enhances d-amino acid incorporation
por: Katoh, Takayuki, et al.
Publicado: (2017)

Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences
por: Pressman, Abe, et al.
Publicado: (2017)

Subtelomeres constitute a safeguard for gene expression and chromosome homeostasis
por: Tashiro, Sanki, et al.
Publicado: (2017)

Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break
por: Wang, Pingping, et al.
Publicado: (2017)

Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease
por: Asano, Kana, et al.
Publicado: (2018)

An interplay of miRNA abundance and target site architecture determines miRNA activity and specificity
por: Brancati, Giovanna, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_9ohr9152jheljc3s5aljf7duri