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Transcript availability dictates the balance between strand-asynchronous and strand-coupled mitochondrial DNA replication
Mammalian mitochondria operate multiple mechanisms of DNA replication. In many cells and tissues a strand-asynchronous mechanism predominates over coupled leading and lagging-strand DNA synthesis. However, little is known of the factors that control or influence the different mechanisms of replicati...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237803/ https://www.ncbi.nlm.nih.gov/pubmed/30239839 http://dx.doi.org/10.1093/nar/gky852 |