A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase

Typically not assisted by proofreading, the RNA-dependent RNA polymerases (RdRPs) encoded by the RNA viruses may need to independently control its fidelity to fulfill virus viability and fitness. However, the precise mechanism by which the RdRP maintains its optimal fidelity level remains largely el...

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Detalles Bibliográficos
Autores principales: Liu, Weichi, Shi, Xiaoling, Gong, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237809/
https://www.ncbi.nlm.nih.gov/pubmed/30239956
http://dx.doi.org/10.1093/nar/gky848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237809/
https://www.ncbi.nlm.nih.gov/pubmed/30239956
http://dx.doi.org/10.1093/nar/gky848

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