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A unique intra-molecular fidelity-modulating mechanism identified in a viral RNA-dependent RNA polymerase
Typically not assisted by proofreading, the RNA-dependent RNA polymerases (RdRPs) encoded by the RNA viruses may need to independently control its fidelity to fulfill virus viability and fitness. However, the precise mechanism by which the RdRP maintains its optimal fidelity level remains largely el...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237809/ https://www.ncbi.nlm.nih.gov/pubmed/30239956 http://dx.doi.org/10.1093/nar/gky848 |