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Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells

Afadin is a cytoplasmic protein of the adherens junctions, which regulates the formation and stabilization of both the adherens and the tight junctions. Aberrant expression of Afadin has been shown in cancer and its loss has been associated with epithelial-to-mesenchymal transition (EMT). EMT is cha...

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Detalles Bibliográficos
Autores principales: Marques, Miguel Sardinha, Melo, Joana, Cavadas, Bruno, Mendes, Nuno, Pereira, Luísa, Carneiro, Fátima, Figueiredo, Ceu, Leite, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237830/
https://www.ncbi.nlm.nih.gov/pubmed/30473688
http://dx.doi.org/10.3389/fmicb.2018.02712