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Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells
Afadin is a cytoplasmic protein of the adherens junctions, which regulates the formation and stabilization of both the adherens and the tight junctions. Aberrant expression of Afadin has been shown in cancer and its loss has been associated with epithelial-to-mesenchymal transition (EMT). EMT is cha...
Autores principales: | Marques, Miguel Sardinha, Melo, Joana, Cavadas, Bruno, Mendes, Nuno, Pereira, Luísa, Carneiro, Fátima, Figueiredo, Ceu, Leite, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237830/ https://www.ncbi.nlm.nih.gov/pubmed/30473688 http://dx.doi.org/10.3389/fmicb.2018.02712 |
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