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Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology

Hepatocellular carcinoma (HCC) develops in the context of chronic inflammatory liver disease and has an extremely poor prognosis. An immunosuppressive tumor microenvironment may contribute to therapeutic failure in metastatic HCC. Here, we identified unique molecular signatures pertaining to HCC dis...

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Detalles Bibliográficos
Autores principales: Okrah, K., Tarighat, S., Liu, B., Koeppen, H., Wagle, M. C., Cheng, G., Sun, C., Dey, A., Chang, M. T., Sumiyoshi, T., Mounir, Z., Cummings, C., Hampton, G., Amler, L., Fridlyand, J., Hegde, P. S., Turley, S. J., Lackner, M. R., Huang, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237857/
https://www.ncbi.nlm.nih.gov/pubmed/30456308
http://dx.doi.org/10.1038/s41698-018-0068-8