Cargando…
Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology
Hepatocellular carcinoma (HCC) develops in the context of chronic inflammatory liver disease and has an extremely poor prognosis. An immunosuppressive tumor microenvironment may contribute to therapeutic failure in metastatic HCC. Here, we identified unique molecular signatures pertaining to HCC dis...
Autores principales: | Okrah, K., Tarighat, S., Liu, B., Koeppen, H., Wagle, M. C., Cheng, G., Sun, C., Dey, A., Chang, M. T., Sumiyoshi, T., Mounir, Z., Cummings, C., Hampton, G., Amler, L., Fridlyand, J., Hegde, P. S., Turley, S. J., Lackner, M. R., Huang, S. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237857/ https://www.ncbi.nlm.nih.gov/pubmed/30456308 http://dx.doi.org/10.1038/s41698-018-0068-8 |
Ejemplares similares
-
A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types
por: Wagle, Marie-Claire, et al.
Publicado: (2018) -
A role for FOXO1 in BCR–ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia
por: Wagle, M, et al.
Publicado: (2016) -
Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter
por: Qu, X, et al.
Publicado: (2016) -
Development of a robust RNA-based classifier to accurately determine ER, PR, and HER2 status in breast cancer clinical samples
por: Wilson, Timothy R., et al.
Publicado: (2014) -
The molecular landscape of high-risk early breast cancer: comprehensive biomarker analysis of a phase III adjuvant population
por: Wilson, Timothy R, et al.
Publicado: (2016)