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T-Cell Exhaustion in Chronic Infections: Reversing the State of Exhaustion and Reinvigorating Optimal Protective Immune Responses

T-cell exhaustion is a phenomenon of dysfunction or physical elimination of antigen-specific T cells reported in human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) infections as well as cancer. Exhaustion appears to be often restricted to CD8+ T cells responses...

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Detalles Bibliográficos
Autores principales: Saeidi, Alireza, Zandi, Keivan, Cheok, Yi Ying, Saeidi, Hamidreza, Wong, Won Fen, Lee, Chalystha Yie Qin, Cheong, Heng Choon, Yong, Yean Kong, Larsson, Marie, Shankar, Esaki Muthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237934/
https://www.ncbi.nlm.nih.gov/pubmed/30473697
http://dx.doi.org/10.3389/fimmu.2018.02569