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A 5′-BODIPY End-label for Monitoring DNA Duplex-Quadruplex Exchange

Fluorescent probes that can distinguish different DNA topologies through changes in optical readout are sought after for DNA-based diagnostics. In this work, the 4,4-difluoro-4-bora-3a, 4a-diaza-s-indacene (BODIPY) chromophore attached to cyanophenyl substituents (BODIPY-CN) has been tethered to the...

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Detalles Bibliográficos
Autores principales: Deore, Prashant S., Soldatov, Dmitriy V., Manderville, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237993/
https://www.ncbi.nlm.nih.gov/pubmed/30442930
http://dx.doi.org/10.1038/s41598-018-35352-0