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c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities

Tumor necrosis factor (TNF) and Toll-like receptor (TLR)3/TLR4 activation trigger necroptotic cell death through downstream signaling complex containing receptor-interacting protein kinase 1 (RIPK1), RIPK3, and pseudokinase mixed lineage kinase-domain-like (MLKL). However, the regulation of necropto...

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Detalles Bibliográficos
Autores principales: Cao, Mengtao, Chen, Fei, Xie, Ni, Cao, Meng-Yao, Chen, Pengfei, Lou, Qi, Zhao, Yanli, He, Chen, Zhang, Shuyuan, Song, Xinyang, Sun, Yu, Zhu, Weimin, Mou, Lisha, Luan, Shaodong, Gao, Hanchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238001/
https://www.ncbi.nlm.nih.gov/pubmed/30442927
http://dx.doi.org/10.1038/s41419-018-1189-2