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Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells

Background: Chemotherapy is the main treatment for triple-negative breast cancer (TNBC), which lack molecular markers for diagnosis and therapy. Cancer cells activate chemoresistant pathways and lead to therapeutic failure for patients with TNBC. Several kinases have been identified as chemoresistan...

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Detalles Bibliográficos
Autores principales: Tzeng, Yen-Dun Tony, Liu, Pei-Feng, Li, Ju-Yueh, Liu, Li-Feng, Kuo, Soong-Yu, Hsieh, Chiao-Wei, Lee, Cheng-Hsin, Wu, Chih-Hsuan, Hsiao, Michael, Chang, Hong-Tai, Shu, Chih-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238227/
https://www.ncbi.nlm.nih.gov/pubmed/30473665
http://dx.doi.org/10.3389/fphar.2018.01285