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High-resolution mapping of centromeric protein association using APEX-chromatin fibers

BACKGROUND: The centromere is a specialized chromosomal locus that forms the basis for the assembly of a multi-protein complex, the kinetochore and ensures faithful chromosome segregation during every cell division. The repetitive nature of the underlying centromeric sequence represents a major obst...

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Detalles Bibliográficos
Autores principales: Kyriacou, Eftychia, Heun, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238281/
https://www.ncbi.nlm.nih.gov/pubmed/30445992
http://dx.doi.org/10.1186/s13072-018-0237-6