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Influence of exogenous growth hormone administration on circulating concentrations of α-klotho in healthy and chronic kidney disease subjects: a prospective, single-center open case-control pilot study

BACKGROUND: The CKD-associated decline in soluble α-Klotho (α-Klotho) levels is considered detrimental. Some studies suggest a direct induction of α-Klotho concentrations by growth hormone (GH). In the present study, the effect of exogenous GH administration on α-Klotho concentrations in a clinical...

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Detalles Bibliográficos
Autores principales: Adema, Aaltje Y., de Roij van Zuijdewijn, Camiel L. M., Hoenderop, Joost G., de Borst, Martin H., Ter Wee, Piet M., Heijboer, Annemieke C., Vervloet, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238285/
https://www.ncbi.nlm.nih.gov/pubmed/30442108
http://dx.doi.org/10.1186/s12882-018-1114-z