Unfractionated heparin ameliorates pulmonary microvascular endothelial barrier dysfunction via microtubule stabilization in acute lung injury

BACKGROUND: Endothelial barrier dysfunction is central to the pathogenesis of sepsis-associated acute lung injury (ALI). Microtubule (MT) dynamics in vascular endothelium are crucial for the regulation of endothelial barrier function. Unfractionated heparin (UFH) possesses various biological activit...

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Detalles Bibliográficos
Autores principales: Mu, Shengtian, Liu, Yina, Jiang, Jing, Ding, Renyu, Li, Xu, Li, Xin, Ma, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238311/
https://www.ncbi.nlm.nih.gov/pubmed/30442128
http://dx.doi.org/10.1186/s12931-018-0925-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238311/
https://www.ncbi.nlm.nih.gov/pubmed/30442128
http://dx.doi.org/10.1186/s12931-018-0925-6

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