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Metformin causes cancer cell death through downregulation of p53-dependent differentiated embryo chondrocyte 1
BACKGROUND: Metformin is the most commonly used first-line medicine for type II diabetes mellitus. Acting via AMP-activated protein kinase, it has been used for more than 60 years and has an outstanding safety record. Metformin also offers protection against cancer, but its precise mechanisms remain...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238313/ https://www.ncbi.nlm.nih.gov/pubmed/30442142 http://dx.doi.org/10.1186/s12929-018-0478-5 |