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Metformin causes cancer cell death through downregulation of p53-dependent differentiated embryo chondrocyte 1
BACKGROUND: Metformin is the most commonly used first-line medicine for type II diabetes mellitus. Acting via AMP-activated protein kinase, it has been used for more than 60 years and has an outstanding safety record. Metformin also offers protection against cancer, but its precise mechanisms remain...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238313/ https://www.ncbi.nlm.nih.gov/pubmed/30442142 http://dx.doi.org/10.1186/s12929-018-0478-5 |