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Identification of Plasmodium GAPDH epitopes for generation of antibodies that inhibit malaria infection

Plasmodium sporozoite liver infection is an essential step for parasite development in its mammalian host. Previously, we used a phage display library to identify mimotope peptides that bind to Kupffer cells and competitively inhibit sporozoite–Kupffer cell interaction. These peptides led to the ide...

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Detalles Bibliográficos
Autores principales: Cha, Sung-Jae, McLean, Kyle Jarrod, Jacobs-Lorena, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238388/
https://www.ncbi.nlm.nih.gov/pubmed/30456380
http://dx.doi.org/10.26508/lsa.201800111