Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells

Breakdown of serine by the enzyme serine hydroxymethyltransferase (SHMT) produces glycine and one-carbon (1C) units. These serine catabolites provide important metabolic intermediates for the synthesis of nucleotides, as well as methyl groups for biosynthetic and regulatory methylation reactions. Re...

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Detalles Bibliográficos
Autores principales: Lucas, Stephanie, Chen, Guohua, Aras, Siddhesh, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238390/
https://www.ncbi.nlm.nih.gov/pubmed/30456347
http://dx.doi.org/10.26508/lsa.201800036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238390/
https://www.ncbi.nlm.nih.gov/pubmed/30456347
http://dx.doi.org/10.26508/lsa.201800036

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