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Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers

BACKGROUND: Comprehensive mutational profiling data now available on all major cancers have led to proposals of novel molecular tumor classifications that modify or replace the established organ- and tissue-based tumor typing. The rationale behind such molecular reclassifications is that genetic alt...

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Detalles Bibliográficos
Autores principales: Heim, Daniel, Montavon, Grégoire, Hufnagl, Peter, Müller, Klaus-Robert, Klauschen, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238410/
https://www.ncbi.nlm.nih.gov/pubmed/30442178
http://dx.doi.org/10.1186/s13073-018-0591-9