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Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers
BACKGROUND: Comprehensive mutational profiling data now available on all major cancers have led to proposals of novel molecular tumor classifications that modify or replace the established organ- and tissue-based tumor typing. The rationale behind such molecular reclassifications is that genetic alt...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238410/ https://www.ncbi.nlm.nih.gov/pubmed/30442178 http://dx.doi.org/10.1186/s13073-018-0591-9 |